OM MANI PADME HUM

Om (A-U-M) Body, speech, mind
Mani (Jewel)  Bhodicita
Padmi (Lotus)  Wisdom
Hum (One)   Indivisibility, Unity

Thus the six syllables, Om Mani Padme Hum, mean that, in dependence on the practice of a path which is an indivisible union of method and wisdom, you can transform your impure body, speech and mind into the exalted body, speech and mind of a Buddha